我和我爸的十七岁是双男主吗 - 我和我爸的十七岁是什么关系

赵立兴　博士　副研究员

微生物学

云南大学生命科学学院省微生物研究所

办公室/试验室：微生物研究所503室

电话： 13708724832

电子函件 (E-mail): zlx70@163.com, lixingzhao@ynu.eu.cn

简介

1994年毕业于安徽农业大学，获农学学士学位；1997年毕业于中国林业科学研究院，获理学硕士学位；2000年毕业于中国科学院沈阳应用生态研究所，获理学博士学位。2000年－2007年在昆明制药集团公司研究开发院工作，任新药研发工程师；2007－2008年在威斯康星大学麦迪逊分校（University of Wisconsin-Madison）做访问学者，与美国著名Prof. Ben Shen合作从事微生物发酵生理、活性代谢产物及生物合成研究工作；2008年供职于云南大学生命科学学院我和我爸的十七岁，从事微生物药物资源与利用方面的研究工作。已在Organic Letters，Journal of Natural Products，Ecological Engineering，Journal of Agricultural and Food Chemistry，Methods in Enzymology，The Journal of Antibiotics，Natural Product Research，International Journal of Systematic and Evolutionary Microbiology，Annals of Microbiology，Journal of Ginseng Research，Plant Disease，Planta Medica等国际期刊发表研究论文40余篇。

研究领域―― 微生物药物资源开发利用

1. 微生物药物资源收集及筛选　微生物药物在临床和农业生产中都占据着重要的位置。从微生物资源中发现新型的微生物药物是解决耐药性的一个重要途径。因此，收集筛选具有药物用途的微生物资源，是微生物新药研究开发的基础，具有重大的意义。

2. 生物活性天然产物的发现及结构鉴定　微生物产生大量的生理活性物质，是临床使用的抗感染、抗肿瘤等药物的重要来源；在农业和畜牧业生产中也占有很高的比重。从各种环境下收集到的活性菌株，通过探索其发酵生理特性，优化发酵条件，探索其生物活性物质，从而为微生物资源利用打下物质基础。

3．微生物资源的综合利用　相对于植物、动物而言，微生物对人类来说可是功能具大，且可以无限复制使用。农杆菌、白僵菌等可以直接用于农林病害防治、发酵及酿酒微生物可以带来美味食物等等。因此，微生物资源的综合利用，对于开发微生物资源、服务于社会和人类健康，是研究微生物的最终目的。

教育经历

1990年-1994年安徽农业大学林学系，本科/农学学士

1994年-1997年中国林业科学研究院资源昆虫研究所，研究生/理学硕士

1997年-2000年中国科学院沈阳应用生态研究所，研究生/理学博士

工作经历

2000年-2007年昆明制药集团股份有限公司，工程师；主要从事中药新药研究开发工作。

2007年-2008年美国威斯康星大学麦迪逊分校药学院，访问学者；主要从事微生物生理与代谢研究。

2008年8月-至今云南大学生命科学学院省微生物研究所，助理研究员，副研究员

荣誉奖励

2009年云南省自然科学一等奖（放线菌系统学，李文均，张玉琴，唐蜀昆，职晓阳，姜怡，王永霞，田新朋，陈华红，赵立兴，段若玲，姜成林）

2013年入选云南大学第四批“中青年骨干教师培养计划”

科研项目

拮抗三七根腐病病原真菌的放线菌代谢产物及其作用机制，国家基金（主持，21562045）

嗜盐放线菌新物种抗肿瘤活性代谢产物研究，国家基金（主持，21062028）

嗜盐放线菌新种发酵条件的优化与抗肿瘤活性成分分析，教育部归国留学人员科研启动基金（主持，2010年第39批）

具有转化喜树碱能力的喜树内生菌株的筛选，云南大学校基金（主持，2010ZD001）

一株具有细胞毒的耐盐放线菌代谢研究，云南大学校基金（主持，2008YB01）

Natural Products from Under-explored Microorganisms，美国NIH基金（参与，1P41GM086184-01A1）

从云南特境放线菌新物种中发现抗肿瘤新活性化合物及其作用机制研究，国家基金（参与，U0932601）

新型抗肿瘤化合物自溶霉素的生物合成，云南省基金重点（参与，2011FA005）

授权专利

1. 李一青，戎贺，赵立兴，徐丽华，一种新四聚肽化合物及其制备方法，ZL201410018290.2

2. 鲁涛，尹敏，赵立兴，韩秀林，沈奔，敲除氧-甲基转移酶基因获得格尔德霉素衍生物的方法，ZL201110405183.1

3. 李文均，胡松楠，魏云林，唐蜀昆，赵立兴，姜成林，徐丽华，高温木聚糖酶的制备方法，ZL20091009434.4

发表的论文

一、 通讯作者

1. Ming Hu, Qi-Ling Li, Ya-Bin Yang, Kai Liu, Cui-Ping Miao, Li-Xing Zhao^*, Zhong-Tao Ding. Koninginins R-S from the endophytic fungus Trichoderma koningiopsis. Natural Product Research. 2017, 31(7):835-839　(IF: 1.057)

2. You-Kun Zheng, Cui-Ping Miao, Hua-Hong Chen, Fang-Fang Huang, Yu-Mei Xia, You-Wei Chen, Li-Xing Zhao^*. Endophytic fungi harbored in Panax notoginseng: diversity and potential as biological control agents against host plant pathogens of root-rot disease. Journal of Ginseng Research. 2016, doi:10.1016/j.jgr.2016.07.005 (IF: 3.898)

3. Kai Liu, Yabin Yang, Jin-Lian Chen, Cui-Ping Miao, Qiang Wang, Hao Zhou, You-Wei Chen, Yi-Qing Li, Zhong-Tao Ding, Li-Xing Zhao^*. Koninginins N-Q, polyketides from the endophytic fungus Trichoderma koningiopsis harbored in Panax notoginseng . Natural Products and Bioprospecting. 2016, 6:49-55

4. Jin-Lian Chen, Kai Liu, Cui-Ping Miao, Shi-Zhong Sun, You-Wei Chen, Li-Hua Xu, Hui-Lin Guan, Li-Xing Zhao^*. Salt-tolerance of endophytic Trichoderma koningiopsis YIM PH30002 and its volatile organic compounds (VOCs) allelopathic activity against phytopathogens associated with Panax notoginseng. Annals of Microbiology. 2016, 66(3):981-990 (IF: 1.232)

5. Kai Liu, Ya-Bin Yang, Jin-Lian Chen, Cui-Ping Miao, You-Wei Chen, Li-Hua Xu, Zhong-Tao Ding, Li-Xing Zhao^*. Koningiopisins A-H, polyketides with synergistic antifungal activities from the endophytic fungus Trichoderma koningiopsis. Planta Medica. 2016, 82(4):371-376 (IF: 1.99)

6. You-Kun Zheng, Xin-Guo Qiao, Cui-Ping Miao, Kai Liu, You-Wei Chen, Li-Hua Xu, Li-Xing Zhao^*. Diversity, distribution and biotechnological potential of endophytic fungi. Annals of Microbiology. 2016, 66(2):529-542 (IF: 1.232)

7. Jin-Lian Chen, Shi-Zhong Sun, Cui-Ping Miao, Kai Wu, You-Wei Chen, Li-Hua Xu, Hui-Lin Guan, Li-Xing Zhao^*. Endophytic Trichoderma gamsii YIM PH30019: a promising biocontrol agent with hyperosmolar, mycoparasitism and antagonistic activities of induced volatile organic compounds on root-rot pathogenic fungi of Panax notoginseng. Journal of Ginseng Research. 2016, 40(4):315-324(IF: 3.898)

8. Cui-Ping Miao, Qi-Li Mi, Xin-Guo Qiao, You-Kun Zheng, You-Wei Chen, Li-Hua Xu, Hui-Lin Guan, Li-Xing Zhao^*. Rhizospheric fungi of Panax notoginseng: diversity and antagonism to host phytopathogens. Journal of Ginseng Research. 2016, 40:127-134

(IF: 3.898)

9. Ze-Yan Fan, Cui-Ping Miao, Xin-Guo Qiao, You-Kun Zheng, Hua-Hong Chen, You-Wei Chen, Li-Hua Xu, Li-Xing Zhao^*, Hui-Lin Guan. Diversity, distribution, and antagonistic activities of rhizobacteria of Panax notoginseng . Journal of Ginseng Research. 2016, 40:97-104

(IF: 3.898)

10. Zi-Jun Xiong, Cui-Ping Miao, You-Kun Zheng, Kai Liu, Wen-Jun Li, Wei-Hong Liu, Li-Hua Xu, Li-Xing Zhao^*. Stackebrandtia endophytica sp. nov., an actinobacterium isolated from Tripterygium wilfordii. International Journal of Systematic and Evolutionary Microbiology. 2015, 65(6): 1709-1713. (IF: 2.439)

11. Pei Cao, Jing Yang, Cui-Ping Miao, Yi-Jun Yan, Ya-Tuan Ma, Xiao-Nian Li, Li-Xing Zhao^*, Sheng-Xiong Huang^*. New Duclauxamide from Penicillium manginii YIM PH30375 and Structure Revision of the Duclauxin Family. Organic Letters. 2015, 1146-1149. (IF: 6.732)

12. Cui-Ping Miao, Xin-Guo Qiao, You-Kun Zheng, You-Wei Chen, Li-Hua Xu, Hui-Lin Guan, Li-Xing Zhao^*. First report of Fusarium flocciferum causing root rot of Sanqi (Panax　notoginseng) in Yunnan, China. Plant Disease. 2015, 99(11):1650 (IF: 3.192)

13. Kai Liu, Youkun Zheng, Cuiping Miao, Zijun Xiong, Lihua Xu, Huilin Guan, Yabin Yang, Lixing Zhao^*. The antifungal metabolites obtained from the rhizospheric Aspergillus sp. YIM PH30001 against pathogenic fungi of Panax notoginseng. Natural Product Research. 2014, 28(24):2334-2337 (IF: 1.057)

14. Shouzheng Tian, Yabin Yang^*, Kai Liu, Zijun Xiong, Lihua Xu and Lixing Zhao^*. Antimicrobial metabolites from a novel halophilic actinomycete Nocardiopsis terrae YIM 90022. Natural Product Research. 2014, 28(5):344-346 (IF: 1.057)

15. Yang Feng, Xuexiu Chang, Lixing Zhao, Xiuping Li, Wenjun Li, Yi Jiang.Nanaomycin A methyl ester, an actinomycete metabolite: algicidal activity and the physiological response of Microcystis aeruginosa. Ecology Engineering. 2013, 53: 306-312. (IF: 2.74)

16. Li-Bing Yang, Li-Xing Zhao.New triterpenoids from the leaves of Photinia serrulata. Journal Chemistry Research. 2008, 613-614

二、 第一作者

1. Li-Xing Zhao, Li-Hua Xu, Cheng-Lin Jiang. Methods for the study of endophytic microorganisms from traditional Chinese medicine plants. Methods in Enzymology. 2012, 517: 3-21. (IF: 2.088)

2. Li-Xing Zhao, Sheng-Xiong Huang, Shu-kun Tang, Cheng-Lin Jiang, Yanwen Duan, John A. Beutler, Curtis J. Henrich, James B. McMahon, Tobias Schmid, Johanna S. Blees, Nancy H. Colburn, Scott R. Rajski, Ben Shen. Actinopolysporins A-C and tubercidin as a Pdcd4 stabilizer from the halophilic actinomycete Actinopolyspora erythraea YIM 90600. Journal of Natural Products. 2011, 74(9): 1990-5. (IF: 2.74)

3. Wen-Yong Zhu, Li-Xing Zhao, Guo-Zhen Zhao, Xue-Wei Duan, Sheng Qin, Jie Li, Li-Hua Xu, Wen-Jun Li. Plantactinospora endophytica sp. nov., an actinomycete isolated from Camptotheca acuminata Decne., reclassification of Actinaurispora siamensis as Plantactinospora siamensis comb. nov. and emended descriptions of the genus Plantactinospora and Plantactinospora mayteni. International Journal of Systematic and Evolutionary Microbiology. 2012, 62(10): 2435-42. (IF: 2.439)

4. Jianwei Dong, Lixing Zhao, Le Cai, Haixian Fang, Xiuhua Chen, Zhongtao Ding. Antioxidant activities and phenolics of fermented Bletilla formosana with eight plant pathogen fungi. Journal of Bioscience and Bioengineering. 2014, 118(4):396-399 (IF: 1.964)

5. Hao Zhou, Lixing Zhao, Wei Li, Yabin Yang, Lihua Xu, Zhongtao Ding. Anti-Mycobacterium tuberculosis Active Metabolites from an Endophytic Streptomyces sp. YIM65484. Records of Natural Products. 2015, 9:196-200 (IF: 0.765)

三、其他

1. Ju-cheng Zhang, Ya-Bin Yang, Guang-Yi Chen, Xiao-Zhan Li, Ming Hu, Bang-Yan Wang, Bao-Hui Ruan, Hao Zhou, Li-Xing Zhao, Zhong-Tao Ding. 8′-epimer of herbicidin F and its congeners from Streptomyces sp. YIM 66142. The Journal of Antibiotics. 2017, 70(3):313-316 (IF: 2.173)

2. Wei Li, Xueqiong Yang, Yabin Yang, Rongting Duan, Guangyi Chen, Xiaozhan Li, Qiling Li, Shaohuan Qin, Shuquan Li, Lixing Zhao, Zhongtao Ding.Anti-phytopathogen, multi-target acetylcholinesterase inhibitory and antioxidant activities of metabolites from endophytic Chaetomium globosum. Natural Product Research. 2016, DOI:10.1080/14786419.2015.1129328 (IF: 1.057)

3. Xiaohui Yan, Huiming Ge, Tingting Huang, Hindra, Dong Yang, Qihui Teng, Ivana Crnov?i?, Xiuling Li, Jeffrey D. Rudolf, Jeremy R. Lolunan, Yannick Gansemans, Xiangcheng Zhu, Yong Huang, Li-Xing Zhao, Yi Jiang, Filip van Nieuwerburgh, Christoph Rader, Yanwen Duan, Ben Shen. Strain Prioritization and Genome Mining for Enediyne Natural Products. mBio. 2016, 7(6):e02104-e02116 (IF: 6.975)

4. Wei Li, Ya-Bin Yang, Xue-Qiong Yang, Hui-Ding Xie, Zhi-Hui Shao, Hao Zhou, Cui-Ping Miao, Li-Xing Zhao, Zhong-Tao Ding. Novel isochroman dimers from Stachybotrys sp. PH30583: fermentation, isolation, structural elucidation and biological activities. Planta Medica. 2016, DOI: 10.1055/s-0042-119650(IF: 1.99)

5. Zhikai Guo, Guohui Pan, Zhengren Xu, Dong Yang, Hindra, Xiangcheng Zhu, Yong Huang, Li-Xing Zhao, Yi Jiang, Yanwen Duan, Ben Shen. New isofuranonaphthoquinones and isoindolequinones from Streptomyces sp. CB01883. The Journal of Antibiotics. 2016, doi:10.1038/ja.2016.122(IF: 2.173)

6. Ming Ma, Mostafa E. Rateb, Dong Yang, Jeffrey D. Rudolf, Xiangcheng Zhu, Yong Huang, Li-Xing Zhao, Yi Jiang, Yanwen Duan, Ben Shen. Germicidins H-J from Streptomyces sp. CB00361. The Journal of Antibiotics. 2016, doi:10.1038/ja.2016.100(IF: 2.173)

7. Yabin Yang, Fangfang Yang, Lixing Zhao, Rongting Duan, Guangyi Chen, Xiaozhan Li, Qiling Li, Shaohuan Qi, Zhongtao Ding. A new polyoxygenated farnesylcyclohexenone from Fungus Penicillium sp. Natural Product Research. 2016, 30(1):65-68 (IF: 1.057)

8. Ming Ma, Mostafa E. Rateb, Qihui Teng, Dong Yang, Jeffrey D. Rudolf, Xiangcheng Zhu, Yong Huang, Li-Xing Zhao, Yi Jiang, Xiuling Li, Christoph Rader, Yanwen Duan, Ben Shen. Angucyclines and angucyclinones from Streptomyces sp. CB01913 featuring C-ring cleavage and expansion. Journal of Natural Products. 2015, 2471-2480 (IF: 3.662)

9. Wei Li, Xueqiong Yang, Yabin Yang, Lixing Zhao, Lihua Xu, Zhongtao Ding. A new anthracycline from endophytic Streptomyces sp. YIM66403. The Journal of Antibiotics,2015, 68:216-219 (IF: 2.173)

10. Yiqing Li, Li Han, He Rong, Liya Li, Lixing Zhao, Longxia Wu, Lihua Xu, Yi Jiang, Xueshi Huang. Diastaphenazine, a new dimeric phenazine from an endophytic Streptomyces diastaticus subsp. ardesiacus. The Journal of Antibiotics. 2015, 68:210-212 (IF: 2.173)

11. Yabin Yang, Fangfang Yang, Cuiping Miao, Kai Liu, Qiling Li, Shaohuan Qin, Lixing Zhao, Zhongtao Ding. Antifungal metabolites from the rhizospheric Penicillium sp. YIM PH 30003 associated with Panax notoginseng. Phytochemistry Letters. 2015, 11:249-253 (IF: 1.353)

12. Wei Li, Xueqiong Yang, Yabin Yang, Shaohuan Qin, Qiling Li, Lixing Zhao, Zhongtao Ding. A new natural nucleotide and other antibacterial metabolites from an endophytic Nocardia sp. Natural Product Research. 2015, 29(2):132-136(IF: 1.057)

13. Xueqiong Yang, Tianfeng Peng, Yabin Yang, Wei Li, Jie Xiong, Lixing Zhao, Zhongtao Ding. Antimicrobial and antioxidant activities of a new benzamide from endophytic Streptomyces sp. YIM 67086. Natural Product Research, 2015, 29:331-335(IF: 1.057)

14. Hindra, Tingting Huang, Dong Yang, Jeffrey D. Rudolf, Pengfei Xie, Guangbo Xie, Qihui Teng, Jeremy R. Lohman, Xiangcheng Zhu, Yong Huang, Li-Xing Zhao, Yi Jiang, Yanwen Duan, Ben Shen. Strain prioritization for natural product discovery by a high-throughput real-time PCR method. Journal of Natural Products. 2014, 77(10):2296-2303 (IF: 3.662)

15. Pengfei Xie, Ming Ma, Mostafa E. Rateb, Khaled A. Shaaban, Zhiguo Yum Sheng-Xiong Huang, Li-Xing Zhao, Xiangcheng Zhu, Yijun Yan, Ryan M. Peterson, Jeremy R. Lohman, Dong Yang, Min Yin, Jeffrey D. Rudolf, Yi Jiang, Yanwen Duan, Ben Shen. Biosynthetic potential-based strain prioritization for natural product discovery: a showcase for diterpenoid-producing actinomycetes. Journal of Natural Products. 2014, 77(2):377-387

(IF: 3.662)

16. Xueqiong Yang, Yun Liu, Shuquan Li, Fangfang Yang, Lixing Zhao, Li Peng, Zhongtao Ding. Antimicrobial Metabolites from Endophytic Streptomyces sp. YIM61470. Natural Product Communications. 2014, 9(9):1287-1288 (IF: 0.884)

17. Hao Zhou, Yabin Yang, Xueqiong Yang, Wei Li, Zijun Xiong, Lixing Zhao, Lihua Xu, Zhongtao Ding. A new cyclic tetrapeptide from an endophytic Streptomyces sp. YIM67005. Natural Product Research. 2014, 28(5):318-323 (IF: 1.057)

18. Hao Zhou, Yabin Yang, Tianfeng Peng, Wei Li, Lixing Zhao, Lihua Xu, Zhongtao Ding. Metabolites of Streptomyces sp., an endophytic actinomycete from Alpinia oxyphylla. Natural Product Research. 2014, 28(4):265-267(IF: 1.057)

19. Zi-Jun Xiong, Jin-Li Zhang, Dao-Feng Zhang, Zhi-Li Zhou, Min-Jiao Liu, Wen-Yong Zhu, Li-Xing Zhao, Li-Hua Xu, Wen-Jun Li. Rothia endophytica sp. nov., a novel actinobacterium isolated from Dysophylla stellata (Lour.) Benth. International Journal of Systematic and Evolutionary Microbiology. 2013, 63(11): 3964-3969 (IF: 2.439)

20. Wen-Yong Zhu, Jin-Li Zhang, Yu-Li Qin, Zi-Jun Xiong, Dao-Feng Zhang, Hans-Peter Klenk, Li-Xing Zhao, Li-Hua Xu, Wen-Jun Li. Blastococcus endophyticus sp. nov., an actinobacterium isolated from Camptotheca acuminata. International Journal of Systematic and Evolutionary Microbiology. 2013, 63(9): 3269-3273 (IF: 2.439)

21. Shou-Zheng Tian, Xiang Pu, Guorong Luo, Li-Xing Zhao, Li-Hua Xu, Wen-Jun Li, Yinggang Luo. Isolation and characterization of new p-Terphenyls with antifungal, antibacterial, and antioxidant activities from halophilic actinomycete Nocardiopsis gilva YIM 90087. Journal of Agriculture and Food Chemistry. 2013, 61(12): 3006-3012 (IF: 2.857)

22. Jie Li, Guo-Zhen Zhao, Ajit Varma, Sheng Qin, Zhi Xiong, Hai-Yu Huang, Wen-Yong Zhu, Li-Xing Zhao, Li-Hua Xu, Si Zhang, Wen-Jun Li. An endophytic Pseudonocardia species induces the production of artemisinin in Artemisia annua. PLoS One, 2012, 7(12): e51410

(IF: 3.057)

23. Xue-Qiong Yang, Ya-Bin Yang, Hao Zhou, Guang-Wei He, Li-Xing Zhao, Li-Hua Xu, Zhong-Tao Ding. New megastigmane glycoside and alkaloids from Streptomyces sp. YIM 63342. Natural Product Research. 2013, 27(13): 1191-1196 (IF: 1.057)

24. Brad Tebbets, Zhiguo Yu, Douglas Stewart, Li-Xing Zhao, Yi Jiang, Li-Hua Xu, David Andes, Ben Shen, Bruce Klein. Identification of antifungal natural products via Saccharomyces cerevisiae bioassay: insights into macrotetrolide drug spectrum, potency and mode of action. Med Mycol. 2013, 51(3): 280-289 (IF: 2.644)

25. Xueqiong Yang, Yabin Yang, Tianfeng Peng, Fangfang Yang, Hao Zhou, Lixing Zhao, Lihua Xu, Zhongtao Ding. A new cyclopeptide from endophytic Streptomyces sp. YIM 64018. Natural Product Communications. 2013, 8(12): 1753-1754 (IF: 0.884)

26. Hao Zhou, Yabin Yang,Jucheng Zhang, Tianfeng Peng, Lixing Zhao, Lihua Xu, Zhongtao Ding. Alkaloids from an endophytic streptomyces sp. YIM66017. Natural Product Communications. 2013, 8(10): 1393-1396 (IF: 0.884)

27. Jie Li, Guo-Zhen Zhao, Hai-Yu Huang, Sheng Qin, Wen-Yong Zhu, Li-Xing Zhao, Li-Hua Xu, Si Zhang, Wen-Jun Li, Gary Strobel. Isolation and characterization of culturable endophytic actinobacteria associated with Artemisia annua L. Antonie Van Leeuwenhoek. 2012, 101(3): 515-27 (IF: 1.944)

28. Shen Qin, Ji-Hong Jiang, Hans-Peter Klenk, Wen-Yong Zhu, Guo-Zhen Zhao, Li-Xing Zhao, Shu-Kun Tang, Li-Hua Xu, Wen-Jun Li. Promicromonospora xylanilytica sp. nov., an endophytic actinomycete isolated from surface-sterilized leaves of the medicinal plant Maytenus austroyunnanensis. International Journal of Systematic and Evolutionary Microbiology. 2012, 62(1): 84-89 (IF: 2.439)

29. Guo-Zhen Zhao, Jie Li, Wen-Yong Zhu, Shou-Zheng Tian, Li-Xing Zhao, Ling-Ling Yang, Li-Hua Xu, Wen-Jun Li. Rhodococcus artemisiae sp. nov., an endophytic actinobacterium isolated from the pharmaceutical plant Artemisia annua L. International Journal of Systematic and Evolutionary Microbiology. 2012, 62(4): 900-905 (IF: 2.439)

30. Dan Zheng, Li Han, Yiqing Li, Jun Li, He Rong, Qiao Leng, Yi Jiang, Lixing Zhao, Xueshi Huang. Isostreptazolin and sannaphenol, two new metabolites from Streptomyces sannanensis. Molecules. 2012, 17(1): 836-842 (IF: 2.465)

31. Xueqiong Yang, Guangwei He, Lixing Zhao, Yabin Yang, Yun Liu, Lihua Xu, Zhongtao Ding. Two novel phenethylamine alkaloids from Streptomyces sp. YIM10049. Natural Product Communication. 2012, 7(12): 1579-80 (IF: 0.884)

32. Shao-Hua Wu, Li-Xing Zhao, You-Wei Chen, Rong Huang, Cui-Ping Miao, Jiao Wang. Sesquiterpenoids from the endophytic fungus Trichoderma sp. PR-35 of Paeonia delavayi. Chemistry and Biodiversity. 2011, 8(9): 1717-23 (IF: 1.444)

33. Min Yin, Tao Lu, Li-Xing Zhao, Yihua Chen, Sheng-Xiong Huang, Jeremy R. Lohman, Li-Hua Xu, Cheng-Lin Jiang, Ben Shen. The missing C-17 O-methyltransferase in geldanamycin biosynthesis. Organic Letters. 2011, 13(14): 3726-3729 (IF: 6.732)

34. Guo-Zhen Zhao, Jie Li, Wen-Yong Zhu, Xiu-Ping Li, Shou-Zheng Tian, Li-Xing Zhao, Li-Hua Xu, Wen-Jun Li. Pseudonocardia bannaensis sp. nov., a novel actinomycete isolated from the surface-sterilized roots of Artemisia annua L. Antonie Van Leeuwenhoek. 2011, 100(1): 35-42 (IF: 1.944)

35. Sheng-Xiong Huang, Zhiguo Yu, Francis Robert, Li-Xing Zhao, Yi Jiang, Yanwen Duan, Jerry Pelletier, Ben Shen. Cycloheximide and congeners as inhibitors of eukaryotic protein synthesis from endophytic actinomycetes Streptomyces sps. YIM56132 and YIM56141. The Journal of Antibiotics. 2011, 64(1): 163-166 (IF: 2.173)

36. Zhiguo Yu, Li-Xing Zhao, Cheng-Lin Jiang, Yanwen Duan, Lily Wong, Kristopher C. Carver,Linda A. Schuler, Ben Shen. Bafilomycins produced by an endophytic actinomycete Streptomyces sp. YIM56209. The Journal of Antibiotics. 2011, 64(1):159-162 (IF: 2.173)

37. Guo-Zhen Zhao, Jie Li, Hai-Yu Huang, Wen-Yong Zhu, Li-Xing Zhao, Shu-Kun Tang, Li-Hua Xu, Wen-Jun Li. Pseudonocardia artemisiae sp. nov., isolated from surface-sterilized Artemisia annua L. International Journal of Systematic and Evolutionary Microbiology. 2011, 61(5):1061-1065 (IF: 2.439)

38. Zhi Yang, Yabin Yang, Xueqiong Yang, Yong Zhang, Li-Xing Zhao, Lihua Xu, Zhongtao Ding. Sesquiterpenes from the secondary metabolites of Streptomyces sp. (YIM 56130). Chemical and Pharmaceutical Bulletin. 2011, 59(11): 1430-3 (IF: 1.228)

39. Sheng-Xiong Huang, Emily Powell, Scott R. Rajski, Li-Xing Zhao, Cheng-Lin Jiang, Yanwen Duan, Wei Xu, Shen B. Discovery and total synthesis of a new estrogen receptor heterodimerizing actinopolymorphol A from Actinopolymorpha rutilus. Organic Letters. 2010, 12(15): 3525-3527 (IF: 6.732)

40. Sheng-Xiong Huang, Li-Xing Zhao, Shu-Kun Tang, Cheng-Lin Jiang, Yanwen Duan, Ben Shen. Erythronolides H and I, new erythromycin congeners from a new halophilic actinomycete Actinopolyspora sp. YIM90600. Organic Letters. 2009, 11(6): 1353-1356

(IF: 6.732)